The White Paper

Abstract

A comparative genomics multitool for scientific discovery and conservation. 

The Zoonomia Project is investigating the genomics of shared and specialized traits in placental mammals by comparing hundreds of species. We announce completion of the first phase: new genome assemblies for 131 species, nearly doubling the families represented, and whole-genome alignment of 241 species. We find that regions of reduced genetic diversity​are more abundant in species with high extinction risk, discern signals of evolutionary selection at unprecedented resolution, and describe insights enabled by individual reference genomes. By prioritizing phylogenetic diversity and making data available quickly, without restriction, the 200 Mammals Project simultaneously advances medicine and biodiversity conservation.

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